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[Helicobacter pylori and gastric adenocarcinoma].

Identifieur interne : 000093 ( Main/Exploration ); précédent : 000092; suivant : 000094

[Helicobacter pylori and gastric adenocarcinoma].

Auteurs : Dalenda Arfaoui ; Hela Elloumi ; Ahmed Ben Abdelaziz [Tunisie]

Source :

RBID : pubmed:19835277

Descripteurs français

English descriptors

Abstract

BACKGROUND

Accumulating evidence for considering HP as a causal factor for gastric cancer comes from recent epidemiologic studies, the advent of an animal model of gastric cancer and from new insights in to the biological mechanisms for gastric carcinogenesis.

AIM

The purpose of this review is to analyze recent data from the literature on this relationship and try to define what kinds of preventive measures could be proposed

METHODS

We conducted a review of the literature through the interrogation of the MEDLINE database using a query documentary by combining the Boolean (AND) keywords (MeSH) as follows: Helicobacter pylori, stomach neoplasms.

RESULTS

HP infection, host genetic background, food regimen are known to be involved in this cancer. There is no definite clinical evidence of the benefifit of eradication on cancer risk in humans due to the lack of randomized controlled studies in large populations. There fore HP should be eradicated in selected patients, such as patients'relatives with documented gastric cancer as well as patients having another gastrointestinal cancer.


PubMed: 19835277


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<title xml:lang="en">[Helicobacter pylori and gastric adenocarcinoma].</title>
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<name sortKey="Arfaoui, Dalenda" sort="Arfaoui, Dalenda" uniqKey="Arfaoui D" first="Dalenda" last="Arfaoui">Dalenda Arfaoui</name>
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<nlm:affiliation>Service de gastroentérologie. CHU Sahloul, Sousse.</nlm:affiliation>
<wicri:noCountry code="subField">Sousse</wicri:noCountry>
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<author>
<name sortKey="Elloumi, Hela" sort="Elloumi, Hela" uniqKey="Elloumi H" first="Hela" last="Elloumi">Hela Elloumi</name>
</author>
<author>
<name sortKey="Ben Abdelaziz, Ahmed" sort="Ben Abdelaziz, Ahmed" uniqKey="Ben Abdelaziz A" first="Ahmed" last="Ben Abdelaziz">Ahmed Ben Abdelaziz</name>
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<country>Tunisie</country>
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<settlement type="city">Sousse</settlement>
<region type="region" nuts="2">Gouvernorat de Sousse</region>
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<orgName type="university" n="3">Université de Sousse</orgName>
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<name sortKey="Elloumi, Hela" sort="Elloumi, Hela" uniqKey="Elloumi H" first="Hela" last="Elloumi">Hela Elloumi</name>
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<name sortKey="Ben Abdelaziz, Ahmed" sort="Ben Abdelaziz, Ahmed" uniqKey="Ben Abdelaziz A" first="Ahmed" last="Ben Abdelaziz">Ahmed Ben Abdelaziz</name>
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<settlement type="city">Sousse</settlement>
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<orgName type="university" n="3">Université de Sousse</orgName>
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<series>
<title level="j">La Tunisie medicale</title>
<idno type="ISSN">0041-4131</idno>
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<date when="2009" type="published">2009</date>
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<term>Adenocarcinoma (microbiology)</term>
<term>Helicobacter Infections (complications)</term>
<term>Helicobacter pylori (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Stomach Neoplasms (microbiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adénocarcinome (microbiologie)</term>
<term>Helicobacter pylori (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infections à Helicobacter (complications)</term>
<term>Tumeurs de l'estomac (microbiologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en">
<term>Helicobacter Infections</term>
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<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr">
<term>Adénocarcinome</term>
<term>Tumeurs de l'estomac</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en">
<term>Adenocarcinoma</term>
<term>Stomach Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Helicobacter pylori</term>
<term>Humans</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="fr">
<term>Helicobacter pylori</term>
<term>Humains</term>
<term>Infections à Helicobacter</term>
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<front>
<div type="abstract" xml:lang="en">
<p>
<b>BACKGROUND</b>
</p>
<p>Accumulating evidence for considering HP as a causal factor for gastric cancer comes from recent epidemiologic studies, the advent of an animal model of gastric cancer and from new insights in to the biological mechanisms for gastric carcinogenesis.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>AIM</b>
</p>
<p>The purpose of this review is to analyze recent data from the literature on this relationship and try to define what kinds of preventive measures could be proposed</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
</p>
<p>We conducted a review of the literature through the interrogation of the MEDLINE database using a query documentary by combining the Boolean (AND) keywords (MeSH) as follows: Helicobacter pylori, stomach neoplasms.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>HP infection, host genetic background, food regimen are known to be involved in this cancer. There is no definite clinical evidence of the benefifit of eradication on cancer risk in humans due to the lack of randomized controlled studies in large populations. There fore HP should be eradicated in selected patients, such as patients'relatives with documented gastric cancer as well as patients having another gastrointestinal cancer.</p>
</div>
</front>
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<name sortKey="Elloumi, Hela" sort="Elloumi, Hela" uniqKey="Elloumi H" first="Hela" last="Elloumi">Hela Elloumi</name>
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<region name="Gouvernorat de Sousse">
<name sortKey="Ben Abdelaziz, Ahmed" sort="Ben Abdelaziz, Ahmed" uniqKey="Ben Abdelaziz A" first="Ahmed" last="Ben Abdelaziz">Ahmed Ben Abdelaziz</name>
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